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how to understand the score in the Effect of point mutations ?

scofield wang hace 11 años 0
Hello ,professor ,I am a postgraduate from china .Thank you for your contributions to the PredictProtein.It is very convenient to use your website and i think it will help me a lot in my research .After getting the results ,i am confused about the score in the effect of point mutations.how to understand the neutral or no effect? Does it mean that if we mutate the wild amino acid  to the <-50 amino acid ,there will be no or less effect on the protein?besides this ,if  i want to do research on the mutation of a protein ,shoud i choose the dark red amino acid ? This question may be simple ,but i look forward to your certain answer . sorry to bother you .
                                                                                                             Best wishes 
                                                                                                             Scofield  wang